A pH-responsive prodrug for real-time drug release monitoring and targeted cancer therapy.

نویسندگان

  • Shi-Ying Li
  • Li-Han Liu
  • Hui-Zhen Jia
  • Wen-Xiu Qiu
  • Lei Rong
  • Hong Cheng
  • Xian-Zheng Zhang
چکیده

A novel cancer targeting and pH-responsive prodrug was successfully designed and synthesized. This M-prodrug was demonstrated to have real-time drug release monitoring capability based on the concept of contact-mediated quenching between doxorubicin and a coumarin derivative.

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عنوان ژورنال:
  • Chemical communications

دوره 50 80  شماره 

صفحات  -

تاریخ انتشار 2014